منابع مشابه
Chlamydia effector proteins and new insights into chlamydial cellular microbiology.
Chlamydia and Chlamydophila sp. are highly related obligate intracellular bacterial pathogens that cause sexually transmitted diseases, ocular infections and atypical pneumonias. Relatively little is known about the molecular mechanisms by which Chlamydiae manipulate the mammalian host because they are intractable to genetic manipulation. Studies with heterologous expression systems have reveal...
متن کاملNew insights into a persistent problem -- chlamydial infections.
Tissue tropism of clinical ocular and genital Chlamydia trachomatis strains is shown to be linked to the tryptophan synthase genotype. It is suggested that, in the presence of IFN-gamma, which depletes available tryptophan, there exist unique host-parasite interactions that may contribute to persistent chlamydial infection.
متن کاملLack of cell wall peptidoglycan versus penicillin sensitivity: new insights into the chlamydial anomaly.
Intracellular bacterial pathogens enter their hosts surrounded by a membrane-bound vacuole and use a panel of tricks to exploit or evade eukaryotic cell functions (9, 12). Chlamydia inhabits vesicles that do not fuse with lysosomes and remains within these parasitophorous vacuoles (termed inclusions) for the duration of its replication cycle. Although the biogenesis of these vacuoles is still p...
متن کاملNew insights into PTEN.
The functions ascribed to PTEN have become more diverse since its discovery as a putative phosphatase mutated in many human tumors. Although it can dephosphorylate lipids and proteins, it also has functions independent of phosphatase activity in normal and pathological states. In addition, control of PTEN function is very complex. It is positively and negatively regulated at the transcriptional...
متن کاملNew Insights Into Mechanisms
Obesity is strongly associated with hypertension and cardiovascular disease. Several central and peripheral abnormalities that can explain the development or maintenance of high arterial pressure in obesity have been identified. These include activation of the sympathetic nervous system and the renin-angiotensin–aldosterone system. Obesity is also associated with endothelial dysfunction and ren...
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ژورنال
عنوان ژورنال: Microbiology Australia
سال: 2020
ISSN: 1324-4272
DOI: 10.1071/ma20005